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Figure 3 Cardiac Events (Cardiac Death, Congestive Heart Failure, and New Atrial Fibrillation) Under Conservative Management After Diagnosis of Asymptomatic AR

Patients are stratified according to QASE AR grading. The QASE-severe AR is defined as regurgitant volume 60 ml/beat or ERO 30 mm² (yellow line), QASE-mild AR as regurgitant volume <30 ml/beat and ERO <10 mm² (brown line), and QASE-moderate AR (dotted orange line) as larger than mild (regurgitant volume 30 ml/beat or ERO 10 mm²), but not reaching QASE-severe criteria. The 5- and 10-year event rates ± SE are indicated. Note the progressive increase in event rates with the severity of QASE-grading of AR. Abbreviations as in Figure 1.