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Figure 4 Impact of ESVI Level on Cardiac Event Rates After Diagnosis of Asymptomatic AR

Cardiac events (cardiac death, congestive heart failure, and new atrial fibrillation) under conservative management after diagnosis of asymptomatic AR according to the left ventricular end-systolic volume index (ESVI, <45 ml/m² [dotted line] or 45 ml/m² [solid line]) stratified by quantitative AR grading. The left graph indicates cardiac events in patients with QASE-mild or QASE-moderate AR grades. The right graph indicates rates in QASE-severe AR grade. Note the higher cardiac events rates (indicated at 5 and 10 years ± SE) with ESVI 45 ml/m², particularly with QASE-severe AR. Abbreviations as in Figure 1.