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Figure 5 Effect of Age (<50 and 50 Years) on Survival After Diagnosis and Cardiac Events

In each panel, survival or event rates are indicated at 5 and 10 years ± SE. Note the low mortality in patients age <50 years (A, 10-year survival 100%, 91 ± 9%, and 100% in QASE-mild, QASE-moderate, and QASE-severe, respectively), whereas mortality is higher after age 50 years (C) and significantly related to QASE-grading of AR. Cardiac events are significantly different according to QASE grading in patients age <50 (B) and 50 years (D) and are similar irrespective of age with QASE-severe AR (p = 0.84). Abbreviations as in Figure 1.