This Article Figures Only Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Google Scholar Articles by Afonso, L. C. Articles by Abraham, T. P. PubMed Articles by Afonso, L. C. Articles by Abraham, T. P.

Echocardiography in Hypertrophic Cardiomyopathy

The Role of Conventional and Emerging Technologies

Luis C. Afonso, MD, FACC^_*, Juan Bernal, MD^_*, Jeroen J. Bax, MD, Theodore P. Abraham, MD, FACC^,_*

^_* Division of Cardiology, Wayne State University, Detroit, Michigan
Division of Cardiology, University of Leiden, the Netherlands
Division of Cardiology, Johns Hopkins University, Baltimore, Maryland

^_* Reprint requests and correspondence: Dr. Theodore P. Abraham, Johns Hopkins University, 600 North Wolfe Street, Carnegie 568, Baltimore, Maryland 21287 (Email: tabraha3{at}jhmi.edu).

Hypertrophic cardiomyopathy is a relatively common inherited cardiomyopathy that is occasionally challenging to differentiate from hypertensive heart disease and athlete hearts on the basis of morphologic or functional abnormalities alone. Echocardiography has traditionally played a preeminent role in the diagnosis, formulation of management strategies, and the prognostication of this complex disease. In this review, we briefly profile the utility and pitfalls of established echocardiographic modalities and discuss the evolving role of novel echocardiographic imaging modalities such as tissue Doppler, Doppler-based strain, 2-dimensional strain (speckle tracking imaging), and 3-dimensional imaging in the assessment of hypertrophic cardiomyopathy.

Key Words: hypertrophic cardiomyopathy • strain imaging • tissue Doppler

Abbreviations and Acronyms    = systolic myocardial strain   CMR = cardiac magnetic resonance   HCM = hypertrophic cardiomyopathy   LA = left atrial   LV = left ventricular   LVH = left ventricular hypertrophy   LVOT = left ventricular outflow tract   Sa = systolic mitral annular tissue velocity   SAM = systolic anterior motion   SR = strain rate   SRI = tissue Doppler-based strain imaging (SRI)   TDI = tissue Doppler imaging   3D-E = 3 dimensional echocardiography