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J Am Coll Cardiol Img, 2009; 2:648-655, doi:10.1016/j.jcmg.2009.03.001
© 2009 by the American College of Cardiology Foundation
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State-of-the-Art Paper

Left Ventricular Torsion

An Expanding Role in the Analysis of Myocardial Dysfunction

Iris K. Rüssel, MSc*,{dagger},*, Marco J.W. Götte, MD, PhD{dagger}, Jean G. Bronzwaer, MD, PhD{dagger}, Paul Knaapen, MD, PhD{dagger}, Walter J. Paulus, MD, PhD{ddagger}, Albert C. van Rossum, MD, PhD{dagger}

* Department of Physics and Medical Technology, VU University Medical Center, Amsterdam, the Netherlands
{dagger} Department of Cardiology, VU University Medical Center, Amsterdam, the Netherlands
{ddagger} Department of Physiology, and the Institute for Cardiovascular Research (ICaR-VU), VU University Medical Center, Amsterdam, the Netherlands

* Reprint requests and correspondence: Dr. Iris K. Rüssel, Department of Physics and Medical Technology, VU University Medical Center, De Boelelaan 1118, 1081 HV Amsterdam, the Netherlands (Email: i.russel{at}vumc.nl).

During left ventricular (LV) torsion, the base rotates in an overall clockwise direction and the apex rotates in a counterclockwise direction when viewed from apex to base. LV torsion is followed by rapid untwisting, which contributes to ventricular filling. Because LV torsion is directly related to fiber orientation, it might depict subclinical abnormalities in heart function. Recently, ultrasound speckle tracking was introduced for quantification of LV torsion. This fast, widely available technique may contribute to a more rapid introduction of LV torsion as a clinical tool for detection of myocardial dysfunction. However, knowledge of the exact function and structure of the heart is fundamental for understanding the value of LV torsion. LV torsion has been investigated with different measurement methods during the past 2 decades, using cardiac magnetic resonance as the gold standard. The results obtained over the years are helpful for developing a standardized method to quantify LV torsion and have facilitated the interpretation and value of LV torsion before it can be used as a clinical tool.

Key Words: left ventricle • cardiac magnetic resonance • myocardial dysfunction • torsion

Abbreviations and Acronyms
  CAD = coronary artery disease
  CMR = cardiac magnetic resonance
  LV = left ventricle
  MI = myocardial infarction






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