Age-Associated Elongation of the Ascending Aorta in Adults
Jun Sugawara, PhD*, ,*,
Koichiro Hayashi, PhD,
Takashi Yokoi, PhD,
Hirofumi Tanaka, PhD*
* Cardiovascular Aging Research Laboratory, Department of Kinesiology and Health Education, University of Texas at Austin, Austin, Texas
Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan
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Figure 1 Changes in Aortic and Arterial Lengths With Age
The ascending aortic length was positively and strongly associated with age, whereas lengths of the descending aorta and the carotid and iliac arteries were not related to age.
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Figure 2 Associations Among the Ascending Aortic Length, Arterial Stiffness, and Pulse Wave Amplification
The ascending aortic length was positively and significantly associated with carotid-femoral pulse wave velocity (PWV), which was obtained by the 3-dimensional artery tracing on magnetic resonance image (PWVMRI), and brachial/aortic pulse pressure (PP) ratio.
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Figure 3 Comparisons of PWV
Scatter plots (left) and Bland-Altman plots (right). All of the carotid-femoral PWVs obtained with the body surface length measurements were significantly and linearly associated with that obtained by PWVMRI. The PWV estimated with the (car-fem) – (ssn-car) equation was the closest to the line of identity in relation to the PWVMRI with the mean ± SD difference of 35 ± 41 cm/s. car = carotid artery; fem = femoral artery; ssn= suprasternal notch; umb = umbilicus; other abbreviations as in Figure 2.
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