Dobutamine Cardiac Magnetic Resonance Results Predict Cardiac Prognosis in Women With Known or Suspected Ischemic Heart Disease
Eric L. Wallace, DO*,
Timothy M. Morgan, PhD ,
Thomas F. Walsh, MD*,
Erica Dall'Armellina, MD*,
William Ntim, MD, FACC*,
Craig A. Hamilton, PhD ,
W. Gregory Hundley, MD, FACC*, ,*
* Department of Internal Medicine (Cardiology Section), Wake Forest University School of Medicine, Winston-Salem, North Carolina
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina
Department of Biomedical Engineering, Wake Forest University School of Medicine, Winston-Salem, North Carolina
Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina
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Figure 1 Kaplan-Meier Survival Plots Indicating the Proportion of Women Free From Cardiac Events Versus Time
Women with inducible LVWM abnormalities are indicated by the red lines, and individuals without inducible LVWM abnormalities are indicated by the gold lines. As shown, those individuals without inducible LVWM abnormalities experienced fewer cardiac events (any, top; hard, bottom) compared with individuals with inducible LVWM abnormalities. LVWM = left ventricular wall motion; MI = myocardial infarction.
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Figure 2 Univariable and Multivariable Predictors for Cardiac Events
Univariable and multivariable analyses displaying hazard ratios ± 95% confidence intervals (x-axis) for developing MI or cardiac death (A), and any cardiac events (B). This model includes risk factors for coronary arteriosclerosis and myocardial infarction. As shown, a stress-induced left ventricular wall motion abnormality is an independent predictor of MI and cardiac death, and any cardiac event after accounting for known risk factors for cardiac events. BMI = body mass index; COPD = chronic obstructive pulmonary disease; MI = myocardial infarction; WMA = wall motion abnormalities.
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