OCT Assessment of Thin-Cap Fibroatheroma Distribution in Native Coronary Arteries
Kenichi Fujii, MD*,*,
Daizo Kawasaki, MD*,
Motomaru Masutani, MD ,
Takahiro Okumura, MD,
Takafumi Akagami, MD,
Tsuyoshi Sakoda, MD,
Takeshi Tsujino, MD*,
Mitsumasa Ohyanagi, MD,
Tohru Masuyama, MD*
* Cardiovascular Division, Hyogo College of Medicine, Nishinomiya, Japan
Division of Coronary Heart Disease, Hyogo College of Medicine, Nishinomiya, Japan
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Figure 1 OCT in Culprit and Nonculprit Lesions
(A) Optical coherence tomography (OCT) image of the culprit lesion with lipid-rich (L) plaque covered by a thin-fibrous cap (53.3 µm) (arrowheads) indicates thin-cap fibroatheroma (TCFA). (B, C, E, and F) TCFAs were also observed in the nonculprit segments. (D) OCT image of a fibrous plaque showing a homogeneous and signal-rich interior was observed.
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Figure 2 Frequency of TCFAs According to Distance From Coronary Ostium
The frequency of 94 thin-cap fibroatheromas (TCFAs) according to distance from each coronary ostium is shown for the left anterior descending artery (LAD), the left circumflex artery (LCx), and the right coronary artery (RCA). Most LAD and LCx TCFAs tend to cluster in the proximal segments of the artery.
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Figure 3 Frequency Distribution of TCFA at Culprit and Nonculprit Lesions
The frequency distribution of thin-cap fibroatheromas (TCFAs) according to distance from each coronary ostium is shown for the left anterior descending coronary artery (LAD), the left circumflex coronary artery (LCx), and the right coronary artery (RCA). Culprit and nonculprit lesions are shown separately. The distribution pattern was similar in culprit TCFAs as compared with nonculprit TCFAs.
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Figure 4 Frequency of Ruptured Plaques According to Distance From Each Coronary Ostium
The frequency of ruptured plaques according to distance from each coronary ostium is shown. The distribution pattern of ruptured plaques was similar to that of thin-cap fibroatheromas. Most left anterior descending coronary artery (LAD) ruptured plaques were located in the proximal segments of the artery. Right coronary artery (RCA) ruptured plaques were evenly distributed throughout the entire coronary length. LCx = left circumflex coronary artery.
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Figure 5 Frequency Distribution of TCFAs and Non-TCFAs Located in the LAD According to Distance From Coronary Ostium
The frequency distribution of thin-cap fibroatheromas (TCFAs) and non-TCFAs located in the left anterior descending coronary artery (LAD) according to distance from each coronary ostium. The distribution pattern in the left anterior descending artery was significantly different between 26 TCFAs and 27 non-TCFAs. The average distance from each plaque to LAD ostium was significantly shorter in TCFAs compared to non-TCFAs.
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