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Figure 1 Example of Measurements for Subendocardial WT
Apical 4-chamber view of real-time myocardial contrast echocardiography with contrast pulse sequencing (Siemens Acuson Sequoia, Mountain View, California) was obtained from a patient with significant left anterior descending coronary artery disease during dobutamine stress. Subendocardial wall thickening (WT) within the apex was measured off-line with commercially available software. The end-diastolic and -systolic wall thickness for transmural WT was measured on the pre-MCR images (the first cardiac cycle after the high mechanical index impulse; left panels) as the distance between the endocardial border (arrow) delineated with left ventricular cavity contrast and the epicardial border (arrow). Subendocardial WT was measurable only if a subendocardial perfusion defect was present (arrows) during the replenishment period (MCR; right panels). See the text for calculation formula. ED = end-diastole; ES = end-systole; MCR= myocardial contrast replenishment.
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