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Figure 1 Documentation of Hibernating Myocardium
All swine underwent unipolar voltage (UPV) mapping (top panel), myocardial blood flow (MBF) measurements with microspheres (middle panel), and transthoracic echocardiography (bottom panel) before myocardial injection of either phVEGF125 or saline. The UPV scores from the Noga map in the ameroid territory were reduced compared with those in the remote myocardium but in the viable range. MBF in cc/g/min was mildly reduced in the ameroid territory compared with that in the remote myocardium. The percent wall thickening in the ameroid territory was reduced compared with that in the remote myocardium. These findings of abnormally functioning but viable myocardium fulfill the criteria for hibernation.
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