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Figure 7 [123I]Gluco-RGD Uptake Versus Angiogenesis
Graph shows percent injected dose (ID) per gram of tissue for [123I]Gluco-RGD plotted versus lectin staining as percent area for vascular endothelial growth factor-injected animals (yellow triangles) and saline injected (orange squares). Although the relationship is significant, there is not a perfect separation between the 2 groups. One saline-injected animal showed no focal hotspot in the myocardium but showed a higher level of background activity for I-123. One of the vascular endothelial growth factor-injected experiments had low uptake of [123I]Gluco-RGD, which corresponded to lower levels of angiogenesis by lectin staining. RGD = arginine-glycine-aspartic acid.
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