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Figure 2 Receiver-Operating Characteristic Curve Analysis
A receiver operating characteristic curve analysis was used to explore the sensitivity and specificity of threshold values of myocardial T2* for left ventricular dysfunction. Using a T2* threshold value of 9 ms, sensitivity = 1 and specificity = 0.86 for a MRI EF <50% (A), sensitivity = 0.77 and specificity = 0.85 for a MRI EF <55% (B), sensitivity = 1 and specificity = 0.83 for echocardiographic EF <50% (C), and sensitivity = 0.71 and specificity = 0.84 for an echocardiographic EF <55% (D). Thus myocardial T2* had a strong relationship with EF and appears to be a promising approach for predicting the development of heart failure and for iron chelator dose adjustment. Abbreviations as in Figure 1.
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