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Figure 4


Figure 4 Time Sequence Analysis of LV Flow During Ejection and IVR Period in Normal Subjects

During ejection (A to C), the direction of the contrast-vector flow was from left ventricular (LV) apex to LV outflow tract. After the aortic valve closure, in the early isovolumic relaxation (IVR) period, the direction of flow reversed from LV base to apex. During mid-late IVR period (E and F), the nonvertical columnar flow was seen directed from base to apex (early ejection: 16 ms after aortic valve opening [A]; mid-ejection: 118 ms after aortic valve opening [B]; late ejection: 245 ms after aortic valve opening [C]; IVR: 32 ms, 80 ms, and 112 ms after aortic valve closure [D to F]). See Online Video 2.





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