|Trial Name (Ref. #)||Target Population||SAQ Findings||Other Symptom Findings|
|Improvement at Follow-up||Difference by Randomization|
|CRESCENT (36)||N = 350||Both testing arms reported improvement in angina stability/frequency and disease perception at 1 yr||1-yr improvement in angina frequency for coronary CTA vs. exercise ECG (p = 0.012) but not for other SAQ subscales||1-yr angina-free rates: 39% for and 25% for coronary CTA vs. exercise ECG (p = 0.012)|
|CAPP (37)||N = 488||Both testing arms reported improvement in angina stability and frequency and QOL at 1 yr but no p values reported||1-yr improvement in angina stability and QOL for coronary CTA vs. exercise ECG (p = 0.028, p = 0.041) but not for other SAQ subscales||1-yr emergency department visit leading to hospitalization (p = 0.009) and CAD outpatient visit (p = 0.036) rates higher for exercise ECG vs. coronary CTA|
|PROMISE (35)||N = 5,985||Both testing arms reported significant improvements in SAQ subscales at 6 months and through 2 yrs||No difference by randomization across SAQ subscales through 2 yrs|
|SCOT-HEART (19)||N = 4,146||Both testing arms reported significant improvement in angina stability and frequency at 6 weeks||No difference by randomization in angina stability (p = 0.22) and frequency (p = 0.21) at 6 months||No difference by randomization in hospitalization for chest pain (p = 0.51)|
|WOMEN (33)||N = 503||Not reported||Not reported||2-yr angina-free rates: 60% and 65% for exercise ECG vs. SPECT (p = 0.25)|
CAPP = Cardiac CT for Assessment of Pain and Plaque; QOL = quality of life; SAQ = Seattle Angina Questionnaire; other abbreviations as in Table 1.