|Test Outcome||Downstream Diagnostic Test|
|Diagnostic conclusive||Intermediate risk†||FFRCT|
|Low risk‡||No additional testing§|
|Diagnostic inconclusive||—||Myocardial perfusion imaging|
|>0.80||No additional testing§|
CTA = computed tomography angiography; FFRCT = coronary computed tomography angiography–derived fractional flow reserve; ICA = invasive coronary angiography.
↵∗ Patients with left main, 3-vessel disease, and/or high-grade proximal left anterior descending artery stenosis.
↵† Patients with 1 or 2 intermediate coronary stenoses (lumen reduction 30% to 70%).
↵‡ Patients with no coronary disease or with maximum coronary stenosis <30%.
↵§ Optimal medical treatment was recommended. If coronary artery disease was present, statin, aspirin, and/or antianginal medication were generally prescribed or recommended via the general practitioner.