|First Author (Ref. #)||Year||Inclusion||Exclusion||Primary Endpoints|
|Maron (18)||2008||HCM patients presenting to Tufts Medical Center and Minneapolis Heart Institute Foundation||Significant atherosclerotic CAD (>50% stenosis in 1 major artery); no patients with prior myectomy||Occurrence of heart failure symptoms, LV systolic dysfunction, adverse cardiovascular events|
|Rubinshtein (17)||2010||HCM patients who underwent CE-MRI at Mayo Clinic||Previous septal myectomy or ablation; MRI performed without IV gadolinium||HCM genes status, severity of symptoms, degree of ventricular ectopy on Holter ECG, subsequent SCD, appropriate ICD therapies|
|O'Hanlon (16)||2010||HCM patients referred for CMR at Royal Brompton Hospital||Significant CAD (>50% stenosis), previous myocardial infarction, prior gradient reduction therapy||Cardiovascular death, unplanned cardiovascular admission, sustained VT/VF, appropriate ICD discharge|
|Bruder (15)||2010||Patients with known or suspected HCM presenting to Essen and Stuttgart for workup||CAD, aortic stenosis, amyloidosis, hypertension, prior septal ablation or myectomy||All-cause mortality, cardiac mortality|
CAD = coronary artery disease; CE = contrast enhanced; CMR = cardiac magnetic resonance; ECG = electrocardiogram; HCM = hypertrophic cardiomyopathy; ICD = implantable cardioverter-defibrillator; IV = intravenous; LV = left ventricular; MRI = magnetic resonance imaging; SCD = sudden cardiac death; VF = ventricular fibrillation; VT = ventricular tachycardia.