Author + information
- Received April 24, 2014
- Revision received June 11, 2014
- Accepted June 26, 2014
- Published online November 1, 2014.
- Hector M. Garcia-Garcia, MD, PhD∗∗ ( )(, )
- Patrick W. Serruys, MD, PhD∗,
- Carlos M. Campos, MD∗,†,
- Takashi Muramatsu, MD, PhD∗,
- Shimpei Nakatani, MD∗,
- Yao-Jun Zhang, MD, PhD∗,
- Yoshinobu Onuma, MD, PhD∗ and
- Gregg W. Stone, MD, PhD‡
- ∗Thoraxcenter, Erasmus, Rotterdam, the Netherlands
- †Heart Institute (InCor), University of São Paulo Medical School, São Paulo, Brazil
- ‡Columbia University Medical Center and Cardiovascular Research Foundation, New York, New York
- ↵∗Reprint requests and correspondence:
Dr. Hector M. Garcia-Garcia, Thoraxcenter—Erasmus Medical Center, z120 Dr Molerwaterplein 40, 3015 GD Rotterdam, the Netherlands.
Bioresorbable vascular scaffolds (BRS) represent a novel approach to provide transient vessel support to drug-delivery capability without the long-term limitations of metallic drug-eluting stents (DES). The technology has the potential to overcome many of the safety concerns associated with metallic DES and possibly even convey further clinical benefit. In particular, the BRS are designed to provide short-term lumen support, and after being completely bioresorbed, eliminate the permanent caging typical of metallic DES. However, this technology has required new imaging modalities and methodologies for its assessment because the design, degradation rate, loss of mechanical property, and drug deliverability may affect its safety and efficacy. We provide an overview of all existing methods for assessing bioresorbable devices, from noninvasive to invasive, from light to sound based, and from morphological to functional parameters.
- bioresorbable scaffolds
- intravascular ultrasound
- multislice computed tomography
- optical coherence tomography
Dr. Stone has served as a consultant to Reva Medical. All other authors have reported that they have no relationships relevant to the content of this paper to disclose.
- Received April 24, 2014.
- Revision received June 11, 2014.
- Accepted June 26, 2014.
- American College of Cardiology Foundation