JACC: Cardiovascular Imaging
State-of-the-Art Paper
T1 MappingBasic Techniques and Clinical Applications
Andrew J. Taylor, Michael Salerno, Rohan Dharmakumar and Michael Jerosch-Herold
Table 1
Table 1
Comparison of T1-Imaging Techniques
| Signal-to-Noise Ratio | Spatial Resolution | T1 Maps (Images in Same Phase) | *T1 Prep Type | Temporal or TI Resolution | Acquisition Time | T1 Accuracy | T1 Precision | Additional Consideration | |
|---|---|---|---|---|---|---|---|---|---|
| Multi-BH IR-FLASH | ++ | ++ | Yes but on different BHs | IR | ++ | 10 BH | ++ | ++ | Negligible MT and T2 effects due to GRE readout |
| Segmented Look-Locker | + | + | No | IR | +++ | ∼20 HB | ++ | ++ | Negligible MT and T2 effects due to GRE readout |
| MOLLI | ++ | ++ | Yes | IR | ++ | 17 HB | ++ | ++ | Potential bias from T2, and MT effects due to SSFP readout |
| shMOLLI | ++ | ++ | Yes | IR | ++ | 9 HB | ++ | ++ | Potential bias from T2, and MT effects due to SSFP readout; conditional fitting |
| MOLLI variants (e.g., 5[3]3) | ++ | ++ | Yes | IR | ++ | 9–12 HB | ++ | ++ | Potential bias from T2, and MT effects due to SSFP readout |
| SASHA | ++ | ++ | Yes | SR | ++ | 11 HB | +++ | + | Relatively small MT effects; limited systematic biases |
BH = breath-hold; FLASH = fast low angle shot; GRE = gradient echo; IR = inversion recovery; MOLLI = modified Look-Locker sequence; MT = magnetization transfer; SASHA = saturation recovery single-shot acquisition; shMOLLI = shortened modified Look-Locker technique; SR = saturation recovery; SSFP = steady-state with free precession imaging; T1 = time constant for recovery of longitudinal magnetization; T2 = time constant for loss of transverse magnetization.
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