Author + information
- Received November 2, 2015
- Revision received January 8, 2016
- Accepted January 14, 2016
- Published online December 1, 2016.
- Asbjørn Mathias Scholtens, MDa,∗ (, )
- Laurens E. Swart, MDb,
- Hein Jan Verberne, MD, PhDc,
- Wilco Tanis, MD, PhDd,
- Marnix G.E.H. Lam, MD, PhDe and
- Ricardo P.J. Budde, MD, PhDb
- aDepartment of Nuclear Medicine, Meander Medical Center, Amersfoort, the Netherlands
- bDepartment of Radiology, Erasmus Medical Center, Rotterdam, the Netherlands
- cDepartment of Nuclear Medicine, Academic Medical Center, Amsterdam, the Netherlands
- dDepartment of Cardiology, HagaZiekenhuis, the Hague, the Netherlands
- eDepartment of Radiology and Nuclear Medicine, University Medical Center, Utrecht, the Netherlands
- ↵∗Reprint requests and correspondence:
Dr. Asbjørn Mathias Scholtens, Department of Nuclear Medicine, Meander Medical Center, Maatweg 3, 3813TZ Amersfoort, the Netherlands.
- computed tomography
- fluorodeoxyglucose F18
- heart valve prosthesis
- positron emission tomography
Recently, 18F-fluorodeoxyglucose positron emission tomography with low-dose computed tomography for attenuation correction and anatomical correlation (18F-FDG-PET/CT) has seen increasing use to help diagnose prosthetic heart valve (PHV) endocarditis. Based on the available evidence, 18F-FDG-PET/CT has even been incorporated in the latest European Society of Cardiology Endocarditis Guidelines (1). As this is still a novel indication for 18F-FDG-PET/CT, the boundaries between normal and abnormal findings are relatively undefined. We present a number of variations (Figures 1, 2, 3, 4, 5, and 6) that could lead to misdiagnosis and need to be taken into account when reading 18F-FDG-PET/CT in patients suspected for PHV endocarditis. Awareness of these variants specifically in the context of suspected PHV endocarditis and cardiovascular infection in a broader sense is pivotal, as this may prevent false-positive or false-negative 18F-FDG-PET/CT readings.
Drs. Swart and Budde are supported by a grant from the Dutch Heart Foundation (NHS 2013T071). All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.
- Received November 2, 2015.
- Revision received January 8, 2016.
- Accepted January 14, 2016.
- American College of Cardiology Foundation
- Habib G.,
- Lancellotti P.,
- Antunes M.J.,
- et al.
- Scholtens A.M.,
- Verberne H.J.,
- Budde R.P.,
- Lam M.G.