Author + information
- Received December 22, 2015
- Revision received January 20, 2016
- Accepted January 21, 2016
- Published online April 1, 2016.
- Lauren A. Baldassarre, MDa,
- Subha V. Raman, MDb,
- James K. Min, MDc,
- Jennifer H. Mieres, MDd,
- Martha Gulati, MDe,
- Nanette K. Wenger, MDf,
- Thomas H. Marwick, MD, PhDg,
- Chiara Bucciarelli-Ducci, MD, PhDh,
- C. Noel Bairey Merz, MDi,
- Dipti Itchhaporia, MDj,
- Keith C. Ferdinand, MDk,
- Carl J. Pepine, MDl,
- Mary Norine Walsh, MDm,
- Jagat Narula, MD, PhDn,
- Leslee J. Shaw, PhDf,∗ (, )
- American College of Cardiology’s Cardiovascular Disease in Women Committee
- aYale University School of Medicine, New Haven, Connecticut
- bThe Ohio State University College of Medicine, Columbus, Ohio
- cWeill Cornell Medical College, New York, New York
- dHofstra Northshore–LIJ School of Medicine, Hempstead, New York
- eThe University of Arizona College of Medicine, Tucson, Arizona
- fEmory University School of Medicine, Atlanta, Georgia
- gMenzies Research Institute, Hobart, Tasmania, Australia
- hUniversity of Bristol, Bristol, United Kingdom
- iCedars-Sinai Medical Center, Los Angeles, California
- jHoag Memorial Hospital Presbyterian Hospital, Newport Beach, California
- kTulane University School of Medicine, New Orleans, Louisiana
- lUniversity of Florida College of Medicine, Gainesville, Florida
- mSt. Vincent Heart Center, Indianapolis, Indiana
- nIcahn School of Medicine at Mount Sinai, New York, New York
- ↵∗Reprint requests and correspondence:
Dr. Leslee J. Shaw, Emory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Room 529, 1462 Clifton Road NE, Atlanta, Georgia 30324.
Declines in cardiovascular deaths have been dramatic for men but occur significantly less in women. Among patients with symptomatic ischemic heart disease (IHD), women experience relatively worse outcomes compared with their male counterparts. Evidence to date has failed to adequately explore unique female imaging targets and their correlative signs and symptoms of IHD as major determinants of IHD risk. We highlight sex-specific anatomic and functional differences in contemporary imaging and introduce imaging approaches that leverage refined targets that may improve IHD risk prediction and identify potential therapeutic strategies for symptomatic women.
Dr. Raman has received research support from Siemens Healthcare; and is a co-inventor and founding member of EXCMR. Dr. Min is a consultant for HeartFlow; is on the Scientific Advisory Board of Arineta; has ownership of MDDX and Autoplak; has a research agreement with GE Healthcare; and is the recipient of grants NIH/NIHLBI R01HL111141, NIH/NIHLBI R01HL115150, NIH/NIHLBI R01HL118019, NIH/NIHLBI U01HL105907, and NPRP09-370-3-089. Dr. Bucciarelli-Ducci is a consultant for Circle Cardiovascular Imaging. Dr. Bairey Merz has received grant support from Gilead, Practive Point, and Medscape. Dr. Ferdinand is a consultant for Amgen, Sanofi, Boehringer Ingelheim, and Eli Lilly; and has received research support from Boehringer Ingelheim. Dr. Pepine received grant UL1TR001427 from the National Center for Advancing Translational Sciences. Dr. Shaw has received the Dean’s Distinguished Faculty Award and the Albert E. Levy Scientific Research Award from Emory University; and has received grant support from the Woodruff Foundation and the Antinori Foundation, and grants NIH-NHLBI R01HL118019-02, R01HL111150, and 1U01HL10556-01; and is a past president of the American Society of Nuclear Cardiology and President-Elect of the Society of Cardiovascular Computed Tomography. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose. Jonathon Leipsic, MD, served as Guest Editor for this paper.
- Received December 22, 2015.
- Revision received January 20, 2016.
- Accepted January 21, 2016.
- American College of Cardiology Foundation