Author + information
- Received March 25, 2015
- Revision received June 8, 2015
- Accepted June 11, 2015
- Published online June 1, 2016.
- Mihai Strachinaru, MDa,∗ (, )
- Nasroolla Damry, MDb,
- Ruth Duttmann, MDc,
- Pierre Wauthy, MD, PhDd,
- Emmanuel Catez, MDa,
- Mirela Lutea, MDa,
- Isabela Costescu, MDe and
- Marielle Morissens, MDa
- aDepartment of Cardiology, Brugmann University Hospital, Brussels, Belgium
- bDepartment of Medical Imaging, Brugmann University Hospital, Brussels, Belgium
- cDepartment of Pathology, Brugmann University Hospital, Brussels, Belgium
- dDepartment of Cardiac Surgery, Brugmann University Hospital, Brussels, Belgium
- eDepartment of Internal Medicine, St. Pierre University Hospital, Brussels, Belgium
- ↵∗Reprint requests and correspondence:
Dr. Mihai Strachinaru, Department of Cardiology, Brugmann University Hospital, 4 Place A. Van Gehuchten Brussels 1020, Belgium.
Contrast echocardiographic perfusion imaging can indirectly demonstrate the existence of local vascularization. This property allows for the differentiation between tumoral processes and thrombi. A quantitative approach is useful to demonstrate the uptake of contrast when the visual assessment is difficult. This method has already been used for the evaluation of cardiac masses with good results even for inexperienced observers (1). It consists of drawing a region of interest within the mass and comparing the evolution of the mean echo intensity with a similar region, generally situated in the adjacent normally perfused myocardium. Another potential approach is the use of parametric maps (2) (color coding of signal intensity). Ultrasound contrast quantification was performed using manufacturer-designed software (Qlab 9, Philips Healthcare, Best, the Netherlands) in typical clinical scenarios (Figures 1, 2, 3, and 4, Online Videos 1, 2, 3, 4, 5, and 6). The time taken to generate the curves of signal intensity for 2 pre-defined 5-mm square regions of interest was about 15 s. A color-coded static image could be computed in 16 s, and a virtual parametric movie in 10 to 20 min.
This iPIX illustrates the use of ultrasound contrast imaging quantification both in transthoracic or transesophageal application, and its role in the decision and disease management. The quantification of contrast intensity could be a reliable and fast diagnostic tool in the evaluation of intracardiac masses.
For supplemental videos and their legends, please see the online version of this article.
The authors have reported that they have no relationships relevant to the contents of this paper to disclose.
- Received March 25, 2015.
- Revision received June 8, 2015.
- Accepted June 11, 2015.
- American College of Cardiology Foundation