Outcome in Dilated Cardiomyopathy Related to the Extent, Location, and Pattern of Late Gadolinium Enhancement
Brian P. Halliday, A. John Baksi, Ankur Gulati, Aamir Ali, Simon Newsome, Cemil Izgi, Monika Arzanauskaite, Amrit Lota, Upasana Tayal, Vassilios S. Vassiliou, John Gregson, Francisco Alpendurada, Michael P. Frenneaux, Stuart A. Cook, John G.F. Cleland, Dudley J. Pennell and Sanjay K. Prasad
Estimated adjusted hazard ratios with 95% confidence intervals (green lines) for (A) all-cause mortality and (B) the sudden cardiac death end-point, per group based on late gadolinium enhancement extent (LGE). Patients are divided into 3 groups based on cut-offs of LGE extent: >0 and <2.55%, ≥2.55 and <5.10%, and ≥5.10%. The hazard ratios for the end-point are positioned at the median LGE extent within each group. A cubic spline model (orange line) has been fitted to the observed data. LVEF = left ventricular ejection fraction; SCD = sudden cardiac death; ASCD = aborted SCD.