Author + information
- Received August 27, 2018
- Revision received October 25, 2018
- Accepted October 25, 2018
- Published online April 17, 2019.
- Sherif F. Nagueh, MD∗ ()
- ↵∗Address for correspondence:
Dr. Sherif F. Nagueh, Methodist DeBakey Heart and Vascular Center, 6550 Fannin, SM-677, Houston, Texas 77030.
• LV diastolic function determines symptoms and predicts outcome in patients with cardiovascular disease.
• Echocardiography is used to assess LV diastolic function, and estimate LV filling pressures.
• Recent American Society of Echocardiography/European Association of Cardiovascular Imaging guidelines were validated against invasive gold standard, with superior accuracy in predicting outcomes.
• LV and left atrial function novel indices and artificial intelligence have potential to advance this field.
Left ventricular diastolic function plays an important role in determining left ventricular filling and stroke volume. Abnormal diastolic function has been recognized in many cardiovascular diseases and is associated with worse outcomes, including total mortality and hospitalizations due to heart failure. Using echocardiography, it is possible to diagnose the presence of diastolic dysfunction and the pathophysiologic mechanisms involved as they affect left ventricular and left atrial structure and function. This review addresses the role of echocardiography in understanding the pathophysiology of diastolic dysfunction, its diagnosis, and utility in predicting outcomes.
Dr. Nagueh has reported that he has no relationships relevant to the contents of this paper to disclose.
- Received August 27, 2018.
- Revision received October 25, 2018.
- Accepted October 25, 2018.
- 2019 American College of Cardiology Foundation
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