Table 1

Patient/Subject Clinical Characteristics and Hemodynamic Parameters

N (male/female)48 (33/15)
Mean age ± SD (range) (yrs)49 ± 15 (23–81)
Cardiac catheterization27
 Coronary anatomy
   3-vessel disease7
   2-vessel disease9
   1-vessel disease3
   All patent8
 Medications
   ACEI/ARB15
   Beta-blockers19
   HMG-CoA reductase inhibitor8
   CCB5
   Oral nitrates15
Electrocardiogram
 Normal25
 NSSTTW22
 IVCD/LBBB5
Hemodynamic parameters (mean ± SD, N = 48)
 Rest
   HR (beats/min)64 ± 11
   SAP (mm Hg)127 ± 17
   RPP (mm Hg/min)8,059 ± 1,866
 Adenosine
   HR (beats/min)88 ± 24
   SAP (mm Hg)123 ± 19
   RPP (mm Hg/min)10,818 ± 3,612

ACEI/ARB = angiotensin-converting enzyme inhibitor/angiotensin receptor blocker; CCB = calcium channel blocker; HMG-CoA = 3-hydroxy-3-methyl-glutaryl-coenzyme A; HR = heart rate; IVCD/LBBB = intraventricular conduction delay/left bundle branch block; NSSTTW = nonspecific ST/T wave abnormalities; RPP = rate–pressure product; SAP = systolic arterial pressure.

  • Five patients with atypical chest pain, 1 with dilated cardiomyopathy, 2 with patent stents.

  • Four patients had both NSSTTW and IVCD/LBBB.

  • p < 0.001 versus rest.