Table 2

Clinical Characteristics and CMR Performance in Patients With LA or LAA Thrombus Detected by Using TEE or Long TI DE-CMR

Subject #Age (yrs)SexCHA2DS2VASc ScoreValvular StatusAnticoagulation TherapyTime Between CMR and TEE (days)Rhythm at CMRLVEF (%)LA Volume Index (ml/m2)CMR StrengthLocation of ThrombusThrombus Size by TEE (cm)Thrombus Size by CMR (cm)CMR Components
Cine-CMRMRALong TI DE-CMR
171F4Prosthetic MV ringWarfarin0AF7754.51.5-TLA (mural)1.81.6++
272F4Prosthetic MV ringDabigatran3AF6665.21.5-TLA (mural)2.32.2++
341M1NoneNo1AF2977.81.5-TLAA2.52.3+++
468F4Moderate MR and AV bioprosthesisWarfarin0SR58194.31.5-TLAA2.11.6+++
544F3Mechanical MVWarfarin0SR3164.71.5-TLAA1.11.4+++
654F2NoneNo0SR8432.13-TLAA0.91.2++
769M3NoneWarfarin0SR4570.13-TLAA0.70.7++
852M3NoneWarfarin3AF2664.51.5-TLAA0.60.6++
958M3NoneWarfarin7AF2956.03-TLAA0.60.5±+
1077M4NoneWarfarin3AF5568.91.5-TLAANone0.6±±
1153M3NoneWarfarin3AF3661.31.5-TLAANone0.5±±

Normal values for LVEF and LA volume index as detailed in Table 1.

+ = thrombus; – = no thrombus; ± = possible thrombus; AV = aortic valve; F = female; LA = left atrial; LAA = left atrial appendage; TI DE-CMR = equilibrium phase delayed enhancement CMR using long inversion time of 600 ms; LVEF = left ventricular ejection fraction; MRA = magnetic resonance angiography; M = male; MR = mitral regurgitation; MV = mitral valve; SR = sinus rhythm; other abbreviations as in Table 1.

  • Thrombus size was measured from its largest dimension by using TEE and long TI DE-CMR.

  • Unlike in subjects #1 through #9, thrombus was not detected by TEE in subjects #10 and #11, resulting in a false-positive interpretation by long TI DE-CMR.