Univariable Analysis | Multivariable Analysis | |||||
---|---|---|---|---|---|---|

Relative Change in 6-Min Walk (95% CI) | p Value | Model 1 (ECV Fraction) | Model 2 (Mid-Wall Fibrosis) | |||

Relative Change in 6-Min Walk (95% CI) | p Value | Relative Change in 6-Min Walk (95% CI) | p Value | |||

Age ≥70 yrs | −50.3 (−83.0 to −17.6) | 0.003 | −41.4 (−74.5 to −8.36) | 0.01 | −50.3 (−83.0 to −17.7) | 0.003 |

Men | −0.81 (−37.7 to 36.1) | 0.97 | −19.9 (−61.3 to 21.6) | 0.35 | −8.88 (−48.5 to 30.7) | 0.66 |

Peak aortic jet velocity, m/s | −12.25 (−30.6 to 6.14) | 0.19 | −14.9 (−35.4 to 5.73) | 0.16 | −11.9 (−32.4 to 8.64) | 0.26 |

LVMi, g/m^{2} | −0.22 (−1.00 to 0.56) | 0.57 | 0.62 (−0.44 to 1.68) | 0.25 | 0.45 (−0.62 to 1.52) | 0.41 |

ECV fraction, % | −9.09 (−15.4 to −2.81) | 0.005 | −9.77 (−17.0 to −2.58) | 0.01 | — | — |

Presence of mid−wall fibrosis | −40.9 (−78.5 to −3.24) | 0.03 | — | — | −45.6 (−89.1 to −2.11) | 0.04 |

CI = confidence interval; other abbreviations as in Tables 2 and 3.