Table 1

Baseline Clinical and CMR Characteristics

No Event (n = 343; 86.8%)Event (n = 52; 13.2%)Total (N = 395; 100%)p Value
Age, yrs57.6 ± 13.263.3 ± 11.858.3 ± 13.10.019
Male226 (65.9)51 (98.1)277 (70.1)<0.001
Body mass index, kg/m21.95 ± 0.232.00 ± 0.201.96 ± 0.230.612
Risk factors
 Diabetes mellitus66 (19.2)12 (23.5)78 (19.7)0.575
 Hypertension201 (58.6)34 (66.7)235 (59.5)0.368
 Current smoker63 (18.4)10 (19.2)73 (18.5)0.849
 Ex-smoker31 (9.0)4 (7.7)35 (8.9)1.000
 Hypercholesterolemia180 (52.5)36 (72)216 (54.7)0.025
 Previous PCI/CABG101 (29.2)34 (65.4)135 (34.2)<0.001
 PCI/CABG within 90 days36 (10.5)4 (7.7)40 (10.1)0.804
 Atrial fibrillation36 (10.5)10 (19.2)46 (11.6)0.100
CMR characteristics
 LVEDV, ml152 (130–183)156 (125–195)153 (129–183)0.462
 Indexed LVEDV, ml/m278 (67–91)79 (65–96)79 (67–91)0.790
 LVESV, ml60 (47–82)65 (41–97)60 (46–84)0.223
 Indexed LVESV, ml/m230 (24–40)32 (22–47)31 (24–41)0.374
 LVEF, %60 (53–66)59 (44–67)60 (52–66)0.121
 LV mass, g107 (88–134)115 (97–134)109 (90–134)0.086
 Indexed LV mass, g/m255 (46–66)60 (50–67)56 (47–56)0.075
 RVEDV, ml149 (126–174)143 (114–170)147 (124–174)0.185
 Indexed RVEDV, ml/m275 (64–87)73 (60–88)31 (23–38)0.178
 RVESV, ml62 (44–77)57 (46–78)61 (44–77)0.671
 Indexed RVESV, ml/m231 (23–39)31 (22–38)31 (23–38)0.610
 LA size, cm223 (20–26)22 (18–27)23 (19–26)0.944
 RA size, cm220 (17–23)21 (18–24)20 (17–23)0.464
 Resting heart rate, beats/min71.8 ± 14.268.7 ± 13.570.8 ± 14.00.182
 Stress heart rate, beats/min96.8 ± 17.490.9 ± 16.195.6 ± 17.60.042
 Rest systolic BP, mm Hg137.9 ± 22.7137.4 ± 22.2137.9 ± 22.40.859
 Rest diastolic BP, mm Hg79.3 ± 12.574.9 ± 10.978.6 ± 12.50.097
 Stress systolic BP, mm Hg132.9 ± 20.6131.8 ± 19.8132.8 ± 20.40.652
 Stress diastolic BP, mm Hg74.5 ± 12.574.5 ± 9.874.5 ± 12.20.763
 Visual ischemic burden, %14.7 ± 29.2
0 (0.0–12.5)
29.6 ± 28.2
25 (0–50)
17.2 ± 29.7
0 (0–25)
<0.001
 MPR ischemic burden, %6.09 ± 14.6
0 (0.0–4.9)
25.1 ± 22.0
23.4 (1.3–39.0)
8.35 ± 16.7
0 (0.0–8.5)
<0.001

Values are mean ± SD, n (%), or median (interquartile range).

BP = blood pressure; CABG = coronary artery bypass grafting; CMR = cardiac magnetic resonance; LA = left atrial; LV = left ventricular; LVEF = left ventricular ejection fraction; LVEDV = left ventricular end-diastolic volume; LVESV = left ventricular end-systolic volume; MPR = myocardial perfusion reserve; PCI = percutaneous coronary intervention; RA = right atrial; RVEDV = right ventricular end-diastolic volume; RVESV = right ventricular end-systolic volume.