Table 1

Demographic and Cardiovascular Risk Factor Distribution of All Smokers LCSE Smokers per the USPSTF

Total MESA Cohort (N = 6,814)All Smokers (N = 3,356)LCSE Smokers (N = 481)p Value (All Smokers vs. LCSE)
Age, yrs62.2 ± 10.262.1 ± 9.965.3 ± 6.9<0.001
Female47.243.539.10.07
Race or ethnicity
 White38.443.249.3<0.001
 Chinese11.85.95.0
 Black27.830.432.6
 Hispanics22.020.513.1
BMI, kg/m228.3 ± 5.528.5 ± 5.428.4± 5.10.70
Cholesterol, mg/dl
 Total194.2 ± 35.7192.5 ± 36.1193.1 ± 38.70.74
 LDL117.2 ± 31.5116.3 ± 31.5117.7 ± 34.80.37
 HDL51.0 ± 14.850.2 ± 14.948.8 ± 14.20.053
 Triglycerides131.6 ± 88.8132.4 ± 92.4134.8 ± 74.00.59
Blood pressure, mm Hg
 Systolic126.6 ± 21.5126.2 ± 21.1128.1 ± 20.60.06
 Diastolic71.9 ± 10.372.3 ± 10.472.3 ± 10.60.99
Cigarette smoking status
 Former36.626.245.7<0.001
 Current13.173.854.3
 Pack-years11.3 ± 20.923.0 ± 24.956.7 ± 28.1<0.0001
Diabetes mellitus11.311.515.00.03
Statin use14.915.219.30.02
Antihypertensive use37.236.740.30.13
ASCVD risk, %13.5 ± 13.114.4 ± 12.817.6 ± 11.9<0.0001
 ≥7.5 10-yr risk56.762.181.5<0.0001
 5.0–7.512.010.4
 ≤5.026.98.1
CAC
 Agatston score146.1 ± 417.2177.1 ± 459.8282.6 ± 576.0<0.0001
 CAC = 050.144.327.9<0.0001
 CAC >049.955.772.1
 CAC 1–30037.540.647.6
 CAC >30012.415.124.5

Values are mean ± SD or %.

ASCVD = atherosclerotic cardiovascular disease; BMI = body mass index; CAC = coronary artery calcium; HDL = high-density lipoprotein; LCSE = lung cancer screening eligible; LDL = low-density lipoprotein; MESA = Multi-Ethnic Study of Atherosclerosis; USPSTF = U.S. Preventive Services Task Force.

  • Student t test.

  • Chi-square test.