Table 2

Baseline Characteristics in the 3 Subgroups of Aortic Phenotype

No-Dilation Phenotype
(n = 39)
Ascending Dilation Phenotype
(n = 76)
Root Dilation Phenotype
(n = 18)
p Value
Age, yrs39 ± 1752 ± 1239 ± 11<0.001
Female10 (26)25 (33)00.007
BSA, m21.85 ± 0.21.83 ± 0.21.93 ± 0.20.13
RN morphotype17 (44)24 (32)00.001
Valve function0.17
 Normal16 (41)40 (53)10 (56)
 Stenosis (≥moderate)13 (33)18 (24)1 (6)
 Regurgitation (≥moderate)10 (26)18 (24)7 (39)
BAV stenosis (any degree)17 (44)41 (54)2 (11)0.003
BAV regurgitation (any degree)28 (72)47 (62)15 (83)0.17
Ejection fraction, %61 ± 460 ± 660 ± 80.42
LVEDd, cm5.2 ± 0.55.2 ± 0.65.7 ± 0.50.011
LVSV, ml87 ± 2490 ± 22109 ± 150.002
IVSTd, cm1.1 ± 0.21.1 ± 0.21.0 ± 0.10.36
COPD05 (7)1 (6)0.26
Hypertension1 (2.6)14 (18)2 (11)0.045
Chronic obstructive arteriopathy4 (10)6 (8)00.52
Mitral valve prolapse/billowing12 (31)16 (21)00.016
AR + MVP association4 (10)7 (9)00.49
Aortic root diameter, cm3.2 ± 0.33.7 ± 0.54.2 ± 0.4<0.0001
STJ diameter, cm2.9 ± 0.43.5 ± 0.53.6 ± 0.4<0.0001
Ascending diameter, cm3.2 ± 0.34.6 ± 0.53.8 ± 0.5<0.0001
Root relative size, cm/m21.7 ± 0.22.0 ± 0.32.2 ± 0.2<0.0001
Ascending relative size, cm/m21.7 ± 0.22.5 ± 0.32.0 ± 0.2<0.0001

Values are mean ± SD or n (%).

Abbreviations as in Table 1.

  • Comparison among phenotypes was by analysis of variance or chi-square test. Italicized p values are statistically significant.