Table 3

Follow-Up Data

Valve MorphotypeAorta Phenotype
RL
(n = 92)
RN
(n = 41)
p Value
RL vs. RN
No Dilation
(n = 39)
Ascending Dilation
(n = 76)
Root Dilation
(n = 18)
p Value Among Phenotypes
Follow-up, yrs3.3 (2.0–5.3)2.4 (1.4–4.8)0.083 (1.8–5.4)3.2 (2–5)2.2 (1.7–5.2)0.75
Growth rate: root, mm/year0 (0–0.31)0 (0–1.2)0.050 (0–0.4)0 (0–0.4)0 (0–0.3)0.27
Growth rate: STJ, mm/year0 (0–0.19)0 (0–0.28)0.340 (0–0.1)0 (0–0.5)0 (0–0)0.79
Growth rate: ascending, mm/year0.2 (0–0.68)0.35 (0–1.3)0.070.2 (0–0.6)0.3 (0–0.7)0.6 (0–1.3)0.43
Progression of root diameter37 (40)18 (44)0.4216 (41)34 (45)5 (28)0.45
Progression of ascending diameter49 (53)24 (58)0.3520 (51)43 (57)10 (56)0.91
Fast progression of root diameter10 (11)15 (37)0.0018 (20)14 (18)3 (17)0.95
Fast progression of ascending diameter17 (18)12 (29)0.129 (24)11 (14)9 (50)0.02
Increase in aortic stenosis degree16 (17)9 (22)0.355 (13)19 (25)1 (6)0.11
Increase in aortic regurgitation degree16 (17)6 (15)0.455 (13)14 (18)3 (17)0.80

Values are median (interquartile range) or n (%). Mann-Whitney and Kruskal-Wallis tests were used to compare follow-up times and growth rates; chi-square test (with Fisher exact correction) was used to compare the percentages of progressing cases and fast progressing cases. Italicized p values are statistically significant.

Abbreviations as in Table 1.