Table 2

Diagnostic Performance of Fully Quantitative, Semiquantitative, and Qualitative Methods To Detect a 70% Stenosis by QCA

MethodAUCSensitivitySpecificityPPVNPV
QP92 (82–97)87 (66–97)93 (81–99)87 (66–97)93 (81–99)
CER78 (66–87)57 (35–77)91 (78–98)76 (49–94)80 (66–90)
SLP82 (71–91)87 (66–97)68 (52–81)59 (41–75)91 (75–98)
INT75 (63–85)83 (61–95)68 (52–81)58 (39–75)88 (72–97)
Duke70 (57–80)87 (66–97)52 (37–68)49 (33–65)88 (70–98)
Clinical78 (66–87)83 (61–95)73 (57–85)61 (42–78)89 (74–97)

Values are % (95% confidence intervals).

AUC = area under the curve; CER = contrast enhancement ratio; INT = upslope integral; NPV = negative predictive value; PPV = positive predictive value; QCA = quantitative coronary angiography; QP = fully quantitative perfusion; SLP = myocardial to left ventricular upslope ratio.

  • p < 0.05 versus QP; statistical comparison of PPV and NPV was not performed.