Table 1

Patient Characteristics

Pioglitazone
(n = 25)
Glimepiride
(n = 22)
p Value
Male19180.897
Age, yrs68.8 ± 7.267.3 ± 9.30.563
Waist circumference, cm64.4 ± 12.565.3 ± 10.80.794
Maximum carotid IMT, mm1.84 ± 0.761.95 ± 1.060.669
Systolic blood pressure, mm Hg128.0 ± 12.3123.5 ± 13.30.239
Diastolic blood pressure, mm Hg70.8 ± 9.069.0 ± 9.30.511
Lipid profile
 LDL cholesterol, mg/dl108.4 ± 23.8117.6 ± 24.80.210
 HDL cholesterol, mg/dl49.9 ± 12.851.3 ± 13.00.723
 Triglycerides, mg/dl105.0 (79.5–125.5)120.0 (74.8–164.0)0.965
Glycemic state
 Fasting plasma glucose, mg/dl121.0 (105.5–140.0)129.0 (119.5–145.5)0.249
 Fasting plasma insulin, μU/ml6.80 (4.55–11.20)4.85 (3.63–8.45)0.157
 Hemoglobin A1c, %6.61 ± 0.736.85 ± 0.640.247
High-sensitivity CRP, mg/dl0.78 (0.34–1.93)0.61 (0.35–1.47)0.466
Risk factor
 Current smoking440.849
 Hypertension23190.88
 Family history of CVD10120.319
Drugs
 ACE-Is or ARBs14160.234
 Beta-blockers1190.831
 Calcium channel blockers15120.706
 Aspirin13160.145
 Statins1390.447

Values are n, mean ± SD, or median (interquartile range).

ACE-I = angiotensin-converting enzyme inhibitors; ARB = angiotensin II receptor blockers; CRP = C-reactive protein; CVD = cardiovascular disease; HDL = high-density lipoprotein; IMT = intima-media thickness; LDL = low-density lipoprotein.