Table 1

Patient Characteristics

Control Subjects
(n = 23)
SLE
(n = 27)
CAD
(n = 25)
p Value
Age, yrs44 ± 1442 ± 1659 ± 9<0.01
Female15 (64)23 (85)†16 (64)0.02
BMI, kg/m226 ± 424 ± 528 ± 60.21
Heart rate, beats/min64 ± 661 ± 758 ± 90.49
Systolic BP, mm Hg123 ± 12129 ± 19139 ± 24<0.01
Diastolic BP, mm Hg81 ± 985 ± 1498 ± 16<0.01
Positive family history of CAD2 (9)3 (11)8 (32)<0.01
Smoking3 (13)5 (20)10 (4)<0.01
Hypercholesterolemia3 (13)5 (20)24 (96)<0.01
Diabetes0 (0)0 (0)5 (23)<0.01
SLEDAI0 (0–3)
History of lupus nephritis12 (44)
Antiphospholipid syndrome12 (44)
eGFR, ml/min102 ± 782 ± 17†78 ± 19<0.01
C-reactive protein, mg/l2.9 ± 1.25.1 ± 3.7†4.9 ± 3.10.04
Erythrocytes sedimentation rate, mm/h<739 ± 21†

Values are mean ± SD or n (%). One-way analysis of variance and Kruskall-Wallis with post-hoc tests for differences ∗for controls vs. coronary artery disease (CAD) patients and †for controls vs. systemic lupus erythematosus (SLE).

BMI = body mass index; BP = blood pressure; CAD = coronary artery disease; ESR = erythrocyte sedimentation rate; eGFR = estimated glomerular filtration rate; SLE = systemic lupus erythematosus; SLEDAI = systemic lupus erythematosus disease activity index.