Table 2

Volumes and Function by Cardiac Magnetic Resonance

Control Subjects
(n = 23)
SLE
(n = 27)
CAD
(n = 25)
p Value
LVED index, ml/m279 ± 2371 ± 18112 ± 41<0.001
LVES index, ml/m233 ± 1139 ± 1468 ± 49<0.001
Ejection fraction, %58 ± 756 ± 1146 ± 180.02
LV mass index, g/m244 ± 2149 ± 1168 ± 310.05
Adenosine perfusion
 Abnormal0 (0)8 (30)22 (88)<0.001
 Inducible ischemia0 (0)0 (0)19 (76)<0.001
 Microvascular disease0 (0)8 (30)0 (0)<0.001
LGE, n present0 (0)11 (41)†20 (80)<0.01
Pulse wave velocity, m/s4.7 ± 2.08.1 ± 3.1†8.7 ± 2.6<0.001
CE intensity0.002
 Mild4 (17)3 (11)2 (8)
 Moderate0 (0)9 (33)8 (32)
 Severe0 (0)15 (66)15 (60)
CE pattern
 Patchy/regional3 (13)3 (11)†19 (76)<0.001
 Generalized1 (4)24 (89)†6 (24)<0.001
CNR3.9 ± 2.56.9 ± 2.5†6.8 ± 2.0<0.001
Total area, mm20.8 (0.6–1.2)3.2 (2.6–4.0)†3.3 (1.9–4.5)<0.001

Values are mean ± SD, n (%), or median (interquartile range). One-way ANOVA and Kruskall-Wallis with post-hoc tests for the differences ∗for controls vs. coronary artery disease (CAD) patients and †for controls vs. systemic lupus erythematosus (SLE).

CE = coronary enhancement; CNR = contrast to noise ratio; LGE = late gadolinium enhancement; LV = left ventricular; LVED = left ventricular end-diastolic; LVES = left ventricular end-systolic; other abbreviations as in Table 1.