Table 1

Infarct Values, LV Function, and LV Volumes by MDCT

ParameterGroupWeek 12Week 24p Value
Infarct size, % of LV massPlacebo13.8 ± 1.316.3 ± 1.60.005
MSC14.3 ± 1.29.9 ± 1.30.001
Total infarct volume, mlPlacebo4.7 ± 0.66.2 ± 0.70.001
MSC4.4 ± 0.43.6 ± 0.50.1
LVED mass, gPlacebo33.6 ± 1.137.5 ± 1.60.02
MSC30.6 ± 1.337.4 ± 2.10.0003
LV ejection fraction, %Placebo33.3 ± 1.429.1 ± 1.50.01
MSC32.6 ± 2.236.9 ± 2.7§0.03
Stroke volume, mlPlacebo19.7 ± 1.619.4 ± 0.80.81
MSC15.1 ± 0.720.6 ± 1.60.004
LVEDV, mlPlacebo60.1 ± 5.767.6 ± 4.10.16
MSC48.1 ± 3.156.3 ± 4.30.01
LVESV, mlPlacebo40.4 ± 4.548.3 ± 3.70.07
MSC33.0 ± 2.936.4 ± 4.10.15

Values are mean ± SEM. MSC (n = 11) versus placebo (n = 8).

LV = left ventricular; LVED = left ventricular end-diastolic; LVEDV = left ventricular end-diastolic volume; LVESV = left ventricular end-systolic volume; MDCT = multidetector computed tomography; MSC = mesenchymal stem cell.

  • p = 0.003.

  • p = 0.01.

  • p = nonsignificant.

  • § p = 0.02.

  • p = 0.047.