Table 1

Demographic Characteristics of the Study Cohort Stratified by Sex

Clinical VariablesAll Patients (N = 405)Women (n = 168)Men (n = 237)p Value
Age, yrs57 ± 1458 ± 1457 ± 140.56
Body mass index, kg/m228 ± 628 ± 728 ± 50.86
Hypertension226 (56)103 (61)123 (52)0.07
Diabetes87 (22)31 (19)56 (24)0.22
Hyperlipidemia228 (57)83 (50)145 (62)<0.05
Tobacco use60 (15)19 (11)41 (17)0.12
Family Hx of CAD104 (26)48 (29)56 (24)0.35
SCOREClinical39 ± 939 ± 1040 ± 90.77
Hx of MI82 (20)24 (14)58 (25)<0.05
Hx of PCI66 (16)13 (8)53 (22)<0.0001
Hx of CABG32 (8)9 (5)23 (10)0.14
Early coronary revascularization43 (11)11 (6.6)32 (14)<0.05
Medications
 Aspirin219 (55)81 (49)138 (60)<0.05
 Beta-blocker214 (53)92 (55)122 (52)0.54
 ACE inhibitor166 (41)60 (36)106 (45)0.08
 Calcium channel blocker68 (17)35 (21)33 (14)0.08
 Statins221 (55)82 (50)139 (59)0.07
Electrocardiography
 Resting heart rate, beats/min69 ± 1471 ± 1568 ± 14<0.01
 Sinus rhythm374 (94)155 (93)219 (94)0.54
 QRS >120 ms33 (8)11 (7)22 (10)0.36
 QTc >400 ms9 (2.3)6 (3.6)3 (1.3)0.17
 Left bundle branch block21(5.3)11 (6.6)10 (4.3)0.37
 Right bundle branch block20(5.0)6 (3.6)14 (6.0)0.35
 LV hypertrophy32 (8.0)13 (7.7)19 (8.2)0.99
 Significant Q waves56 (14)14 (8.3)42 (18)<0.01
 Resting ST changes51 (12.9)20 (12.1)31 (13.5)0.76
 Resting T-wave inversions81 (20.5)27 (16.4)54 (23.5)0.1
CMR variables
 LVEF, %57 ± 1360 ± 1256 ± 13<0.001
 LV mass index, g/m262 ± 1756 ± 1566 ± 18<0.0001
 LVEDVi, ml/m286 ± 2679 ± 2192 ± 27<0.0001
 LVESVi, ml/m239 ± 2433 ± 1943 ± 27<0.0001
 Resting RWMA101 (25.1)25 (15)76 (32.5)<0.0001
 LGE presence119 (30)22 (13)97 (41)<0.0001
 LGE mass, per gram of tissue4.4 ± 111.8 ± 76.2 ± 13<0.0001
 % of LGE, per 10% of LV mass3.3 ± 8.31.8 ± 6.34.4 ± 9.3<0.0001
 Rest perfusion defect53 (13)16 (10)37 (16)0.09
 Stress perfusion defect126 (31)39 (23)87 (37)<0.005
 ISCHEMIA(+)109 (27)36 (21)73 (31)<0.05
 ISCH-SCORE1.3 ± 3.00.9 ± 2.21.6 ± 3.5<0.05
 ISCH-SCORE, ISCHEMIA(+)5.0 ± 4.04.3 ± 2.95.3 ± 4.40.15

Values shown are mean ± SD or n (%).

ACE = angiotensin-converting enzyme; CABG = coronary artery bypass graft; CAD = coronary artery disease; CMR = cardiac magnetic resonance; Hx = history; ISCHEMIA(+) = evidence of ischemia present; ISCH-SCORE = myocardial extent of ischemia; LGE = late gadolinium enhancement; LV = left ventricular; LVEDVi = left ventricular end-diastolic volume index; LVEF = left ventricular ejection fraction; LVESVi = left ventricular end-systolic volume index; MI = myocardial infarction; RWMA = regional wall motion abnormality; PCI = percutaneous coronary intervention; SCOREClinical = clinical risk profile score.