Table 2

Doppler Echocardiographic Variables

NormalGrade 1 (IR)Grade 2 (PN)Grade 3 (RF)p Value
nMean ± SDnMean ± SDnMean ± SDnMean ± SD
E at rest, cm/s2189 ± 161457 ± 108076 ± 155198 ± 21<0.01
A at rest, cm/s2169 ± 181466 ± 248081 ± 185197 ± 24<0.01
E/A at rest211.37 ± 0.44140.94 ± 0.29800.98 ± 0.3511.08 ± 0.44<0.01
Deceleration time at rest, ms20221 ± 3913255 ± 7479241 ± 5051245 ± 560.25
e' at rest, cm/s2110.9 ± 1.2148.7 ± 1.3807.2 ± 1.3516.1 ± 1.3<0.01
a' at rest, cm/s2110.2 ± 1.91411.4 ± 2.4809.6 ± 1.9518.5 ± 2.2<0.01
s', cm/s<0.01
 Rest168.6 ± 1.4119.0 ± 3.1757.3 ± 1.2456.8 ± 1.1
 Peak dose1615.2 ± 3.91114.7 ± 2.37512.1 ± 3.04510.4 ± 2.3
 Δ (peak dose − at rest)166.6 ± 3.7115.7 ± 2.2754.8 ± 2.8453.6 ± 2.1
E/e' at rest218.2 ± 1.6146.6 ± 1.18010.5 ± 1.35116.3 ± 3.3<0.01

a′ = late diastolic mitral annular velocity; e′ = early diastolic mitral annular velocity; s′ = systolic mitral annular velocity; other abbreviations as in Table 1.

  • Analysis of variance (ANOVA);

  • p < 0.05 versus normal by Dunnett's post-hoc test;

  • ANOVA with 1 repeated measure.