Table 3

IVPD at Rest and During Dobutamine Infusion

NormalGrade 1 (IR)Grade 2 (PN)Grade 3 (RF)p Value
nMean ± SDnMean ± SDnMean ± SDnMean ± SD
Total IVPD0.02
 At rest212.80 ± 1.07142.12 ± 0.96802.62 ± 1.08513.15 ± 1.20
 Low dose213.91 ± 2.21142.61 ± 0.96803.92 ± 1.6514.07 ± 1.48
 Peak dose215.00 ± 1.74142.85 ± 1.03803.66 ± 1.48514.23 ± 1.59
 Δ (peak dose − at rest)212.20 ± 1.95140.73 ± 1.33801.04 ± 1.63511.08 ± 1.57
IVPD from LA to mid-LV0.11
 At rest211.58 ± 0.59141.09 ± 0.39801.49 ± 0.57511.86 ± 0.84
 Low dose212.12 ± 0.99141.24 ± 0.38801.87 ± 0.72512.16 ± 0.88
 Peak dose212.29 ± 0.89141.79 ± 0.64801.80 ± 0.71512.37 ± 0.96
 Δ (peak dose − at rest)210.71 ± 0.82140.70 ± 0.84800.31 ± 0.77510.51 ± 1.13
IVPD from mid-LV to LV apex<0.01
 At rest211.40 ± 0.80141.27 ± 0.64801.35 ± 0.76511.52 ± 0.72
 Low dose212.05 ± 1.47141.55 ± 0.79802.27 ± 1.26512.08 ± 0.95
 Peak dose213.12 ± 1.24141.41 ± 0.59802.19 ± 1.04512.14 ± 1.29
 Δ (peak dose − at rest)211.73 ± 1.29140.15 ± 0.72800.84 ± 1.12510.63 ± 1.32

IVPD = intraventricular pressure difference; LA = left atrium; LV = left ventricle; other abbreviations as in Table 1.

  • Analysis of variance with repeated measures;

  • p < 0.05 versus normal by Dunnett's post-hoc test.