Table 4

Improvement in Regional Myocardial Contraction But Not Relaxation After CCM Therapy Defined by Tissue Doppler Imaging

Baseline3 Monthsp Value
Systolic function
 Sm, basal septal (cm/s)2.8 ± 0.93.1 ± 0.90.064
 Sm, basal lateral (cm/s)2.4 ± 1.02.9 ± 1.10.005
 Sm, basal anterior (cm/s)2.3 ± 0.92.8 ± 1.10.024
 Sm, basal inferior (cm/s)2.9 ± 0.93.3 ± 0.9<0.001
 Sm, basal anteroseptal (cm/s)2.2 ± 0.92.8 ± 0.8<0.001
 Sm, basal posterior (cm/s)2.5 ± 0.93.0 ± 1.00.001
Diastolic function
 Em, basal septal (cm/s)3.4 ± 1.93.1 ± 1.60.219
 Em, basal lateral (cm/s)3.5 ± 2.13.6 ± 2.30.815
 Em, basal anterior (cm/s)3.3 ± 2.03.5 ± 1.70.559
 Em, basal inferior (cm/s)3.4 ± 1.53.5 ± 1.50.570
 Em, basal anteroseptal (cm/s)2.5 ± 1.42.8 ± 1.50.191
 Em, basal posterior (cm/s)3.7 ± 2.33.2 ± 1.70.059
 Am, basal septal (cm/s)3.6 ± 1.93.9 ± 2.10.152
 Am, basal lateral (cm/s)2.4 ± 1.62.7 ± 1.60.105
 Am, basal anterior (cm/s)2.7 ± 1.73.3 ± 1.60.015
 Am, basal inferior (cm/s)3.9 ± 2.04.3 ± 2.00.140
 Am, basal anteroseptal (cm/s)2.9 ± 1.53.2 ± 1.70.050
 Am, basal posterior (cm/s)3.0 ± 1.63.2 ± 1.70.369
Dyssynchrony
 Ts-SD (ms)28.2 ± 11.227.9 ± 12.70.809
 Septal to lateral wall delay in Ts (ms)47.9 ± 29.246.1 ± 32.00.741
 Anterior to inferior wall delay in Ts (ms)45.2 ± 27.043.5 ± 28.70.645
 Anteroseptal to posterior wall delay in Ts (ms)36.2 ± 34.235.5 ± 38.70.908
 Te-SD (ms)30.0 ± 18.330.1 ± 20.70.943

Am = myocardial late diastolic velocity at the time of atrial contraction; Em = myocardial early diastolic velocity; Sm = myocardial systolic velocity; Te-SD = standard deviation of the time to peak myocardial early diastolic velocity of the 12 left ventricular segments; Ts-SD = the standard deviation of the time to peak myocardial systolic velocity of the 12 left ventricular segments; Ts = time to peak myocardial systolic velocity; other abbreviations as in Table 1.