Table 1

Clinical and Echocardiographic Characteristics of the Study Population Before and After PMC

Overall (n = 875)Group 1 (n = 189)Group 2 (n = 459)Group 3 (n = 227)p Value Between Groups
Clinical variables
 Age, yrs48 ± 1353 ± 1347 ± 1347 ± 13<0.0001
 Female726 (83%)161 (85%)382 (83%)183 (81%)0.46
 NYHA functional class III/IV657 (75%)155 (82%)333 (72%)169 (75%)0.04
 Sinus rhythm543 (62%)105 (56%)291 (63%)147 (65%)0.11
 Previous commissurotomy130 (15%)30 (16%)64 (14%)36 (16%)0.73
 Cardiothoracic index51 ± 552 ± 551 ± 550 ± 50.0009
Echocardiographic variables
 Before PMC
   Mitral valve area, cm21.08 ± 0.221.09 ± 0.221.07 ± 0.221.08 ± 0.230.55
   Mean gradient, mm Hg10.1 ± 4.59.9 ± 4.210.2 ± 4.710.1 ± 4.10.68
   Mitral regurgitation grade 1 or 2311 (36%)78 (41%)162 (35%)71 (31%)0.10
 After PMC
   Mitral valve area, cm21.94 ± 0.271.77 ± 0.191.93 ± 0.252.10 ± 0.27<0.0001
   Mean gradient, mm Hg4.5 ± 1.85.1 ± 2.14.5 ± 1.74.0 ± 1.6<0.0001
   Mitral regurgitation grade 2184 (21%)42 (22%)111 (24%)31 (14%)0.0006

Data presented are number of patients (%) or mean ± SD.

NYHA = New York Heart Association; PMC = percutaneous mitral commissurotomy.