Table 1

Measurements of Systemic and Renal Hemodynamic Parameters at Baseline and 15 min After Intravenous Infusion of Nesiritide in 16 Patients With HF

VariableMean ± SDp Value
BaselineInfusion
HR (beats/min)79 ± 1681 ± 160.444
SRBP (mm Hg)135 ± 28123 ± 220.003
DRBP (mm Hg)79 ± 1271 ± 10<0.001
MRBP (mm Hg)99 ± 1789 ± 130.002
RAP (mm Hg)9 ± 67 ± 50.061
SPA (mm Hg)55 ± 1949 ± 220.001
DPA (mm Hg)26 ± 822 ± 9<0.001
MPA (mm Hg)36 ± 1231 ± 13<0.001
PCWP (mm Hg)21 ± 815 ± 10<0.001
CO (l/min)3.9 ± 1.24.6 ± 1.60.001
CI (l/min/m2)2.2 ± 0.52.5 ± 0.6<0.001
SVR (dynes·s·cm−5)1,995 ± 5321,563 ± 504<0.001
PVR (dynes·s·cm−5)315 ± 157305 ± 1570.632
VTI (cm/beat)27 ± 1523 ± 150.008
RAD (mm)6.2 ± 0.76.7 ± 0.8<0.001
RVR (dynes·s·cm−5)14,568 ± 7,33413,609 ± 6,6540.45
RBF (ml/min)623 ± 326647 ± 4120.15

CI = cardiac index; CO = cardiac output; DPA = diastolic pulmonary artery (pressure); DRBP = diastolic renal blood pressure; HF = heart failure; HR = heart rate; MPA = mean pulmonary artery (pressure); MRBP = mean renal blood pressure; PCWP = pulmonary capillary wedge pressure; PVR = pulmonary vascular resistance; RAD = renal artery diameter; RAP = right atrial pressure; RBF = renal artery blood flow; RVR = renal vascular resistance; SPA = systolic pulmonary artery (pressure); SRBP = systolic renal blood pressure; SVR = systemic vascular resistance; VTI = velocity-time integral.