Author + information
- Received March 2, 2016
- Revision received March 21, 2016
- Accepted March 24, 2016
- Published online August 24, 2016.
- Nay Aung, MD,
- Filip Zemrak, MD,
- Saidi A. Mohiddin, MBChB, MD and
- Steffen E. Petersen, MD, DPhil, MPH∗ ()
- Barts Heart Centre, William Harvey Research Institute, NIHR Cardiovascular Biomedical Research Unit at Barts, Queen Mary University of London, London, United Kingdom
- ↵∗Reprint requests and correspondence:
Dr. Steffen E. Petersen, Barts Heart Centre, William Harvey Research Institute, NIHR Cardiovascular Biomedical Research Unit at Barts, Charterhouse Square, London, EC1M 6BQ, United Kingdom.
Left ventricular noncompaction (LVNC) is characterized by the presence of an extensive noncompacted myocardial layer lining the cavity of the left ventricle (LV) and potentially leads to cardiac failure, thromboembolism, and malignant arrhythmias (1). LVNC is a heterogeneous clinical condition, which often shows an overlap with other forms of established cardiomyopathy (2). Whether it is a distinct cardiomyopathy or a morphological variant of other types of nonischemic cardiomyopathy is still debated. There are uncertainties regarding its prevalence and incidence, natural history including prognosis, best diagnostic approaches, and management. Cardiac magnetic resonance plays an increasingly important role in detection of noncompacted myocardium and identification of prognostic markers such as late gadolinium enhancement.
We report 2 short cases of related individuals (Figures 1, 2, and 3, Online Videos 1, 2, 3, and 4) with increased LV trabeculations. The key learning points highlight the importance of LV systolic function and pre-test probability in formulating the management plan (Figure 4).
For accompanying videos and their legends, please see the online version of this article.
Dr. Petersen is a consultant to Circle Cardiovascular Imaging. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.
- Received March 2, 2016.
- Revision received March 21, 2016.
- Accepted March 24, 2016.
- American College of Cardiology Foundation
- Arbustini E.,
- Weidemann F.,
- Hall J.L.
- Oechslin E.,
- Jenni R.